The proper functioning of the body depends on the functional interaction between different types of molecules from the same or different groups.
One such group is peptides. These biomolecules are important players in a wide variety of biological processes that are fundamental to the well-being of our organism.
At Nanopep, we have been working for over 30 years with the best international experts in biochemistry and applied molecular biology in the search for short peptides to create innovative products with a high degree of performance and great health benefits.
The result of our extensive experience is our constantly updated catalogue of high quality, certified and safe food supplements and cosmetic products based on short peptides, manufactured in laboratories using the latest production technologies.
Epigenetics is a branch of genetics that deals with the study of all those heritable modifications that lead to changes in gene expression without altering the DNA sequence,
Specifically, epigenetic modifications are carried out by a series of molecules, such as short peptides, which, through specific reactions, attach themselves to or detach from certain parts of the DNA, making them more or less accessible.
Focusing on these effects of natural peptides produced by our bodies, more than 50 years ago in Russia, Prof. Khavinson and his team began studies on short peptides.
They were clear in their minds that since these natural bioregulators had such important activity, this would also apply to synthetic peptide compounds.
Nanopep products are based on Prof. Khavinson’s research, and we currently have a range of around 20 different short peptide products, all of high quality, effectiveness and safety, with many more in the pipeline.
The first thing to consider, when deciding to use peptide-based supplements, is whether you want to use peptides to supplement a specific medical therapy, or to use these powerful molecules to prevent ailments or diseases and to strengthen the body and keep it at a high level of wellness.
In the first case, it is necessary to take specific supplements that act on the disease in progress, while in the second it is possible to target a series of products whose daily intake allows us to replenish the reserves of those natural substances that are fundamental to keeping us in an excellent state of health.
In the last situation, in general, the most commonly used supplements are those that contain active peptides to strengthen the immune system, have anti-ageing effects, regulate biological rhythms and help reduce and control emotional stress.
There are several things to consider when choosing a dietary supplement. Let us consider the four most important ones:
Synthetic peptides can contain varying amounts of impurities, which may result from total/partial oxidation or decomposition of the product, and/or come from foreign chemical substances. The mechanism of action of peptides is very delicate and even the presence of small impurities can compromise their proper functioning and thus render the treatment ineffective.
At Nanopep, we apply critical quality measures in our production processes to avoid the slightest impurity. These measures, applied to all our peptides, minimise the possibility of impurities and maximise the effectiveness of our products.
The quality of a food supplement is the set of characteristics and properties of a product that give it the ability to meet the customer’s implicit or expressed requirements.
Quality Assurance (QA), Quality Control (QC) and Good Manufacturing Practice (GMP) are practices that ensure that analytical methods to determine the structural integrity and purity of peptides are developed and subsequently validated.
To ensure this, we at Nanopep keep a certified Quality Management System (QMS), which is audited yearly by an accredited independent certification body, to guarantee the correct implementation of standard operating procedures that ensure the quality of all our supplements.
Effectiveness is a parameter that must always be taken into account when choosing a peptide-based dietary supplement. Effectiveness is different from efficacy. While efficacy refers to the results of clinical studies, effectiveness refers to actual data on the effects of the product in actual use.
Often a drug that is efficacious in clinical trials is not very effective in actual use. For example, a drug may have high efficacy in increasing melatonin levels, but may be less effective because it causes so many adverse effects that patients stop taking it.
At Nanopep, we not only carry out rigorous testing to ensure that a product meets customer needs and builds brand confidence before it hits the shelves, but we also continuously collect customer feedback and use it to improve products.
Companies that develop, manufacture, sell, market, distribute or import/export their products must first ensure that they meet the regulatory requirements of both the Health Authority (HA) and the Ministry of Health (MoH) of each country. Since countries have specific definitions and classification criteria, it is important to ensure that the product is correctly classified before proceeding with the registration/notification process, as the classification will provide a clear roadmap.
Since Nanopep supplements are distributed worldwide, we make sure that all our products are registered according to the rules in force in the country of destination.
The immune system can be defined as the set of organs, tissues,
cells, that act together to protect the body from various attacks by pathogens, such as bacteria or viruses, parasites or aggressors that develop within the body itself, such as malignant cells (e.g. cancer cells).
The immune system can be subject to various conditions that weaken it; when this happens, it sends us several alarm bells, including:
To strengthen the immunity and avoid falling prey to these annoying and harmful symptoms, we developed NEMOREX® Spray, a dietary supplement based on 2 short peptide bioregulators EW and KE, which show high level of performance:
The health of the heart and of the entire circulatory system is fundamental for the entire organism because the heart is the engine of life, working 24 hours a day and contracting incessantly.
Cardiovascular risk factors are conditions that increase the likelihood of developing a disease of the cardiovascular system and are divided into ‘non-modifiable’ and ‘modifiable’.
Non-modifiable risk factors
We cannot intervene because they are beyond our control. They are:
Modifiable risk factors
They can be reversible:
The dietary supplements CRONOREX® Spray contains the bioregulatory peptide KED, which activates the regeneration and cellular repair of cardiovascular tissue and helps the normalization of the functional state of the cardiovascular system. CRONOREX® Spray also:
The human organism is a highly specialised system for responding
in a sophisticated way to stimuli, through the global coordination of the different biological functions performed by the nervous system.
The central nervous system is such a complex system that abnormalities can occur, leading to disorders and/or diseases that can be very serious.
Migraine, headaches, epilepsy, speech disorders, sleep disorders, encephalitis, meningitis, Alzheimer’s disease, Parkinson’s disease, multiple sclerosis, stroke, dementia, autoimmune diseases are some of the most common neurological diseases.
Nanopep’s EPITALON® supplement is a synthetic peptide consisting of four amino acids (alanine, glutamic acid, aspartic acid and glycine), based on Epithalamin a natural peptide extracted from the pineal gland, which is effective in restoring neuroendocrine regulation in cases of disorders of various origins.
EPITALON® is indicated for the normalisation of neuroendocrine regulation of the fundamental functions of the brain and central nervous system. This high-performance supplement is able to:
In addition, EPITALON® acts as a stimulator of protein synthesis and telomerase activation, thus working as an anti-aging substance.
We breathe in around 12,000 litres of air every day, thereby involuntarily inhaling pollutants such as smoke, viruses and bacteria: the lungs are therefore a very easy target, constantly exposed to attacks from the external environment.
It is therefore essential to maintain and nourish the respiratory tract’s defences, to enable it to react effectively to bacterial and viral attacks, such as those recently experienced with the Covid 19 pandemic.
All the different parts that constitute the respiratory system can be subject to various diseases, such as obstructive, restrictive, vascular or infectious/environmental.
If the respiratory system is weak, free radicals act by impairing the body and causing increased oxidative stress, often associated with inflammatory reactions. This is precisely why it is important to increase antioxidant defences and combat oxidative stress in the body and respiratory system.
ALVEFLEXIN®PLUS boosts the functionality of the cells of the bronchial epithelium through the combination of the peptide AEDL and the peptide KE (VILON®), which has been shown to normalize and enhance the cellular composition of the bronchi in different disease processes through the epigenetic regulation of protein synthesis and cell renewal processes.
ALVEFLEXIN®Plus is one of the most effective products available for preventing premature degeneration of the pulmonary system and can be easily combined with other supplements and medicines and should be used in addition to conventional medical treatments.
The main function of the male genital/reproductive apparatus is the production of sperm necessary for fertilisation of the ovum. The spermatic ducts, seminal vesicles, bulbourethral glands and prostate are the internal structures of the male genital apparatus; the penis and scrotum the external ones.
Prostate and testicular disease is a subject that young men are generally uninterested in because in the collective imagination they are considered typical diseases of a certain age. In reality, this is not necessarily the case and, in any case, care should be taken from a young age because prevention should start early.
Several diseases affect the male genital apparatus, such as:
The three signal bioregulators contained in the special formula of RESIFLEXIN®Plus have proven high efficiency in normalizing the function of the prostate and testes by reducing peptide deficiency and restoring protein synthesis within the cells.
This is due to the high quality ingredients in RESIFLEXIN®Plus, KEDP tetra-peptide, KEDG tetra-peptide and KE di-peptide (VILON®), which normalize and improve the function of the male reproductive system, enhancing the function of the entire genitourinary system and increasing the duration of male youth.
Nanopep’s supplements are easy to use. In the case of the chewable tablets, simply hold them in your mouth until they dissolve. The recommended daily dose is 1 tablet in the morning. If capsules are taken, the dose to use is 1 capsule per day in the morning with a glass of water. For use as a spray, spray 2 or 3 times (depending on the product) under the tongue twice a day for 20 days.
Research on peptides has experienced a breakthrough, not only in terms of scientific interest, but also for the creation of peptide-based products that can alleviate the distress of those suffering from pathological conditions, but also intended as health support to improve quality of life.
The market for peptide-based nutritional supplements is undoubtedly growing, and many companies have jumped on the bandwagon.
While it is true that peptides are natural substances, it is also true that the production of synthetic peptides that mimic the effects of those naturally present in our bodies must necessarily be subject to strict criteria, not only in terms of production, but also in terms of proving effectiveness and, above all, safety.
Since the beginning of our exciting adventure in the world of peptides in the early 1990s, we at Nanopep have considered the health and safety of people to be our first priority.
That is why, in addition to creating an R&D department that works with the best experts to study peptides and their functions, we have devoted a great deal of attention to checking and controlling every aspect of our business.
From the search for the best materials and the most modern production technologies to the control of each step of the production chain, right up to the final product, our commitment enables us to deliver to our users innovative and high quality products, tested and controlled, compliant with current standards and, above all, with very high safety margins.